How does Lion's Mane affect the brain?
If you're looking for a way to improve memory, concentration, and overall brain function, you may have heard of Lion's Mane (Hericium erinaceus) mushroom. But does it really work? Below, we will explore the effectiveness of this mushroom in enhancing cognitive functions and why it might be a valuable addition to Your daily diet.
Clinical Studies: Real Evidence of Effectiveness
One of the most significant studies demonstrating the positive impact of Lion's Mane on cognitive function was conducted with patients suffering from Alzheimer's disease. A study published in the International Journal of Molecular Sciences (Li, et al., 2017) found that Hericium erinaceus extract significantly improved cognitive function in mice with Alzheimer's symptoms by increasing NGF levels and reducing neurodegenerative changes in the brain.
Lion's Mane contains unique bioactive compounds—hericenones and erinacines—that stimulate the production of nerve growth factor (NGF). NGF is a vital protein that supports the growth and regeneration of neurons (brain cells). Neuronal damage and reduced NGF activity are closely linked to various neurodegenerative diseases, including Alzheimer's disease and dementia.
Research suggests that Lion's Mane can accelerate the neuron regeneration process, improving not only brain plasticity but also cognitive functions such as memory and learning by protecting brain cells from oxidative stress.
Alzheimer's Disease Research
One of the most significant studies demonstrating the positive impact of Lion's Mane on cognitive function was conducted with patients suffering from Alzheimer's disease. A study published in the International Journal of Molecular Sciences (Li, et al., 2017) found that Hericium erinaceus extract significantly improved cognitive function in mice with Alzheimer's symptoms by increasing NGF levels and reducing neurodegenerative changes in the brain.
Improvements in Memory and Concentration
Lion's Mane is rich in antioxidants, which protect the brain from damage caused by free radicals and help reduce age-related cognitive decline. Another clinical trial involving people aged 50 to 80 years showed that after taking Lion's Mane for 16 weeks, participants experienced significant improvements in cognitive functions and short-term memory. When the supplement was discontinued, these improvements began to fade, highlighting the importance of sustained usage.
References:
Neurotrophic and Neuroprotective Effects of Hericium erinaceus
Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake
Therapeutic Potential of Hericium erinaceus for Depressive Disorder